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Top2a cell cycle

Web1. jan 2024 · The ubiquitin-proteasome system is also known to regulate levels of TOP2A during the cell cycle (Eguren et al., 2014; Salmena et al., 2001). While numerous … Web23. dec 2024 · 3、scRNA-seq与cell cycle 在分析单细胞数据时，同一类型的细胞往往来自于不同的细胞周期阶段，这可能对下游聚类分析，细胞类型注释产生混淆； 由于细胞周期 …

Untangling the roles of TOP2A and TOP2B in transcription and …

We next performed FRAP analysis to explore how TOP2 proteins exist in the nucleoplasm and nucleolus. Without 2DG/CCCP treatment, a small area in the nucleoplasm of an EGFP-TOP2A-expressing cell was photobleached (Fig. 3a). We observed rapid recovery of fluorescence in the bleached … Zobraziť viac Although TOP2B was reported to accumulate in the nucleoli of ATP-depleted cells, the precise relationship between ATP levels and the subnuclear … Zobraziť viac Next, we examined whether 2DG/CCCP treatment could affect the cytotoxicity of etoposide in comparison with two additional DNA-damaging agents, … Zobraziť viac WebTopoisomerase 2A (TOP2A) is a protein involved in cell proliferation and was recently found to be over-expressed in metastatic PPGL. Aims: To provide support whether TOP2A could … paper form chooser https://shieldsofarms.com

Untangling the roles of TOP2A and TOP2B in transcription and cancer

Web3. aug 2012 · The TOP2A protein, encoded by the TOP2A gene, is a key enzyme of DNA replication, cell-cycle progression, as well as chromosome segregation and a target of … Web27. aug 2024 · Based on the fact that TOP2a can direct and regulate the process of embryonic development ( 10, 25 ), we here attempt to investigate the expression pattern … WebTOP2A. The TOP2A protein is an enzyme that functions to introduce temporary double-stranded breaks into the DNA that are also necessary for DNA replication. From: Cell and … paper forecast

Priming a vascular-selective cytokine response permits CD8+ T-cell …

Category:Proliferating cell nuclear antigen (PCNA): a key factor in DNA ...

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Top2a cell cycle

TOP2A and EZH2 Provide Early Detection of an Aggressive …

Web12. apr 2024 · In conclusion, the results of the present study reveal that TOP2A, ITGA2, PLK1 and CDK1 may act as key genes associated with HCC. Moreover, cell cycle and cell … Web摘要： Cyclin-dependent kinase 1 (CDK1) plays an essential role in cell cycle regulation.However,as mouse Cdk1 embryos die early,the role of CDK1 in regulating the …

Top2a cell cycle

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Web1. jún 2024 · This comparison revealed that cell fate 1 elevated canonical DP marker genes (such as APOD and SOX18) enriched in the GO terms of “tissue morphogenesis” and “epidermis development”, while cell fate 2 elevated genes (such as CENPW and TOP2A) enriched in the GO terms of “mitotic cell cycle process” and “DNA-dependent DNA … Web2. sep 2010 · Topoisomerase II (Top2) is a nuclear enzyme involved in several metabolic processes of DNA. Chemotherapy agents that poison Top2 are known to induce persistent protein-mediated DNA double strand …

Web16 search results for TOP2A. SuperPathway Name Genes Count Relevance Score; 1: Gastric cancer network 2: Genes symbols: TOP2A Web10. dec 2024 · Taken together, these results show that miR-144-3p inhibited growth and promoted apoptosis in glioma cells by targeting TOP2A. Next Article in Journal. ... For PCR, 5 min at 95 °C, followed by 40 cycles of 10 s at 95 °C, 40 s at 60 °C and 30 s at 40 °C. Sequences of primer pairs used in qPCR was the following: IE1 forward, 5 ...

Web11. apr 2024 · Cell cycle-related genes like Ccna2, Ccnb2, Ccnd1, Ccnd2, ... Top2a, and Mki67 to distinguish PBC and other types of KC (Fig. 7 A and B). We found that both in psoriasis model mice and patients, the percentage of PBC was significantly increased compared to controls (Fig. 7 C–F). To further verify the protein expression of CUX1 in … Web2. jún 2024 · Topoisomerase IIα (TOP2A) is a core component of mitotic chromosomes and important for establishing mitotic chromosome condensation. The primary roles of …

WebFrom the PPI network, the top 10 hub genes in SCLC were selected, including topoisomerase IIα, proliferating cell nuclear antigen, replication factor C subunit 4, checkpoint kinase 1, …

Web计算细胞周期评分 首先，我们基于G2/M和S期的经典marker基因的表达，计算每个细胞可能所处的细胞周期的分数。 这些marker基因集应该与它们的表达水平是成反相关的关系， … paper forestry oregonWebMechanismly, TOP2A activates cell cycle progression from G2 to M phase by inhibiting the phosphorylation of CHK1 and promotes Epithelial-to-mesenchymal transition (EMT) … paper form creatorWebTopoisomerase 2A (TOP2A) is a key member of this family that prominently stains along the axis of mitotic chromosomes. Assessing mitotic-specific functions of TOP2A has … paper forex trading