Webb9 dec. 2024 · However, despite its bioavailability, abundance, and functional importance, few studies have investigated the therapeutic targeting of CSP as a novel cancer … Webb27 feb. 2024 · Therefore, plectin has been proposed to serve as a robust cancer biomarker. Given the critical role plectin plays in tissue mechanics, which is a key aspect of cancer …
Targeted inactivation of plectin reveals essential function in ...
WebbTesting newly synthesized drugs for their capability to kill cancer cells in cell culture Bachelor Thesis in Cell Biology Max F. Perutz Laboratories Apr. 2012–Mai 20122 Monate Vienna Assessment... WebbAlthough Plectin-1 IHC has insufficient accuracy to be used as a definitive biomarker for malignant risk in the evaluation of IPMN biopsy or cytological specimens, increased … dr regan illinois bone institute
Unexpected gain of function for the scaffolding protein plectin due …
Webb13 nov. 2024 · University of Houston College of Pharmacy associate professor Gomika Udugamasooriya discovered a new biomarker, plectin, in cancer stem cells that governs … WebbCells sense and respond to mechanical cues from the extracellular matrix (ECM) via integrins. ECM stiffness is known to enhance integrin clustering and response to epidermal growth factor (EGF), but we lack information on when or if these mechanosensitive growth factor receptors and integrins converge intracellularly. Towards closing this knowledge … WebbDevelopment of a phosphoproteomic screen of innate immune signalling : identification and characterisation of a novel phosphorylation of NFkB1/p105 college student project ideas