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The CDCP1 Signaling Hub: A Target for Cancer Detection
SpletEx-vivo lung explants are living, three-dimensional lung tissue slices, also referred to as precision-cut lung slices (PCLS). PCLS contain nearly all cells that are normally present in … The Fraunhofer ITEM offers contract research in the area of human health. … Splet03. jan. 2024 · The functional role of CDCP1 overexpression was assessed taking advantage of ex vivo organoids derived from the CDCP1 pcLSL/+ transgenic mouse model. Furthermore, CDCP1 knockout UC cell lines were generated using CRISPR/Cas9 technology. Interestingly, CDCP1 overexpression significantly induced the activation of MAPK/ERK … mark shoun morristown tn