WebMar 27, 2015 · Dynactin is an essential cofactor for the microtubule motor cytoplasmic dynein-1. We report the structure of the 23-subunit dynactin complex by cryo-electron microscopy to 4.0 angstroms. Our reconstruction reveals how dynactin is built around a filament containing eight copies of the actin-related protein Arp1 and one of β-actin. WebNov 9, 2024 · Dynactin p150 Antibody (12) is an IgG 1 κ mouse monoclonal Dynactin p150 antibody (also designated Dctn1 antibody or p150-glued antibody) suitable for the detection of the Dynactin p150 protein of mouse, rat, human and canine origin by WB, IP and IF. Dynactin p150 Antibody (12) is available as the non-conjugated anti-Dynactin …
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WebMar 29, 2024 · Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein … WebFeb 22, 2008 · In contrast to kinesin, encounters of dynein-dynactin-GFP with Alexa-tau molecules did not induce motor detachment or pausing. Instead, dynein-dynactin tended to reverse direction upon encountering tau (Fig. 2, A and C, and movies S3 and S4). When dynein-dynactin bound within a tau23 patch, it did not rapidly detach like kinesin, but … d felony wisconsin
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WebDigitonin is an natural detergent [2] . 体外研究. ( In Vitro) Digitonin, a detergent that increases cell permeability by binding to cholesterol molecules in the cell membrane, can … WebKIAA0649 antibody 中文名称 KIAA0649蛋白抗体 别 名 1A6/DRIM (down regulated in metastasis) interacting protein; DRIM/UTP20 interacting protein; K0649_HU WebDec 22, 2024 · 马达蛋白是细胞内物质运输颗粒和囊泡的载体,是一类利用ATP水解所产生的化学能量驱动自身沿微管(Microtubule)或微丝(microfilament)定向运动的蛋白。. 马达蛋白根据其作用部位分为两类,微管马达蛋白,包括包括驱动蛋白(Kinesin)与动力蛋白(Dynein)两个家族 ... church wilne water treatment works