WebHigh body weight was not associated with risk of thromboembolism compared with non-high body weight (RR, 0.88; 95% CI, 0.63-1.23). The subgroup of AF patients with high body weight had a lower risk of thromboembolism compared with non-high body weight (RR, 0.43; 95% CI, 0.28-0.67). Bleeding outcomes were comparable for all body weight …
Rationale and impact Venous thromboembolic diseases: …
WebMay 16, 2024 · Data from healthy volunteers and patients with nonvalvular atrial fibrillation (NVAF) or venous thromboembolism (VTE) have shown that increased body weight has a modest effect on apixaban's PK. However, the paucity of exposure data in individuals > 120 kg and the lack of guideline consensus on DOAC use in obese patients continue to raise ... WebMay 19, 2024 · Conclusion: While the published evidence on use of DOACs in patients at extremes of body weight is sparse, apixaban and rivaroxaban appear to have the most … the novick\u0027s stadium rouen
Drug xtrem Dosing in E es of 2013 Body Weight September
WebJun 22, 2024 · Patients at the extremes of body weight (BMI 18.5 and ≥40 kg/m 2) had better safety and efficacy with DOAC as compared to warfarin. Study Questions: What … WebExceptions to the use of eGFR include toxic drugs, in elderly patients and in patients at extremes of muscle mass (see Estimating renal function in patients at extremes of muscle mass and Estimating renal function in elderly patients, ... Ideal body weight (kilograms) = Constant + 0.91 (Height - 152.4) Where: Constant = 50 for men; 45.5 for women; WebMar 26, 2024 · There was little evidence on the comparative effectiveness of different anticoagulants for people at extremes of body weight, and the evidence was limited to … the novi home design center