WebJul 16, 2016 · The CSCs theory. Cancer stem cell (CSC) concept is one the hypothesis proposed to explain the tumor cell heterogeneity. This hypothesis postulates that, like to growth of normal proliferative tissues, growth of tumors or development of a tumor clone is driven by a population of cells endowed with both differentiation abilities and self … WebJun 15, 2012 · Background and aim: Recently, the cancer stem cells (CSCs) theory has been proposed, and CD133 has been suggested as a potential marker of CSCs in various cancer types. In the present study, we aimed evaluate CD133 as a potential marker of colorectal CSCs and, for this purpose, isolated CD133(+) and CD133(-) cells from a …
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