site stats

Cisplatin salt wasting

WebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in cisplatin-resistant cancer cells has become a major obstacle in clinical management of cancers (Amable, 2016 ). WebFeb 16, 2024 · Cisplatin Carboplatin 11% (carboplatin likely lower) SIADH, renal salt wasting (tubular damage) Cyclophosphamide Ifosfamide 9%–52% SIADH BCR-ABL tyrosine kinase inhibitors Imatinib 9%–13% SIADH BRAF and VEGF tyrosine kinase inhibitors Axitinib Sorafenib Brivanib Pazopanib Sunitinib 16%–39% SIADH EGFR …

Renal Salt-Wasting Syndrome in a Patient With Cisplatin-Indu

WebCisplatin induces both inflammation and vascular injury, which further promotes kidney injury. In addition to AKI, cisplatin causes proximal tubulopathy, salt wasting, loss of urinary concentrating ability, and magnesium wasting. View chapter Purchase book T cells in kidney injury and regeneration Li Li, ... WebNov 1, 2003 · In 1988, Hutchison et al reported profound urinary sodium wasting in 7 of 70 patients treated with cisplatin over an 18- month period in 1 institution. 1 All the patients were men with carcinomas (including 1 patient with SCLC) and presented 2-4 months after starting cisplatin-based therapy with signs of vol- ume depletion, urinary salt wasting ... biodiversity and poverty reduction https://shieldsofarms.com

Profound hyponatremia and dehydration: A case of cisplatin …

WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head ... both water restrictions and sodium supplementation may be appropriate when differentiating between diagnoses of renal salt wasting syndrome and syndrome of inappropriate antidiuretic hormone secretion. Fed Pract. 2024 December;38(12 ... WebMay 19, 2024 · Rarely, cisplatin-related hyponatremia may result from Renal Salt Wasting Syndrome ( 33 ). Hypernatremia can also develop with cisplatin due to acquired nephrogenic diabetes insipidus with ensuing … WebFeb 16, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin … biodiversity and wildlands project usa map

PROFOUND HYPONATREMIA AND DEHYDRATION: A CASE OF CISPLATIN INDUCED SALT …

Category:Cisplatin - an overview ScienceDirect Topics

Tags:Cisplatin salt wasting

Cisplatin salt wasting

Frontiers Electrolyte Disorders Induced by …

WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting … WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. During his five-day hospital course, his renal parameters steadily improved, and his serum sodium improved from 124 mEq ...

Cisplatin salt wasting

Did you know?

WebCisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1 mg twice daily, oral salt tablets 1 g QID, sodium bicarbonate tablets … WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head ... both water restrictions and sodium supplementation may be …

WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, …

WebBoth renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for … WebDifferential diagnosis of hyponatremia induced by cisplatin-containing chemotherapy: syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt …

WebMar 1, 2024 · Cisplatin may produce renal salt wasting causing symptomatic orthostatic hypotension and hyponatremia associated with abnormalities of the renin-aldosterone …

WebAug 1, 2024 · Cisplatin (CDDP) is an important anticancer drug. A common side effect of CDDP is renal salt and water-wasting syndrome (RSWS). The origin of RSWS is … biodiversity and sustainabilityWebSep 1, 2002 · (6) The mechanism of cisplatin-induced hyponatremia is thought to be mainly renal salt wasting syndrome (RSWS), (7) (8) (9) (10) (11) (12) (13) and sometimes the syndrome of inappropriate... biodiversity and the challenge of pluralismWebContact ASN. 1401 H St, NW, Ste 900, Washington, DC 20005. [email protected]. 202-640-4660 biodiversity animated gifWebDec 10, 2024 · A 20-year-old man developed renal salt wasting syndrome (RSWS) during treatment with cisplatin for germ cell testicular cancer. The man had non-seminomatous … dahlia knotted sandal loeffler randallWebOct 6, 2016 · In the clinical setting, the most common and important manifestation of cisplatin nephrotoxicity is AKI, which can be progressive and even irreversible. Other renal manifestations include hypomagnesaemia, salt wasting, a … biodiversity and wildlands project mapWebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical... dahlia law group oakland caWeb42%–100% of patients depending on total cisplatin dose and length of exposure. Hypomagnesemia and renal magnesium wasting may persist for up to 6 years after initial dose (5). Renal salt wasting syndrome has been reported in up to 10% of patients, manifesting as hyponatremia and severe ortho-static hypotension in the setting of high … biodiversity and zoonotic diseases