Chromomycin-a3

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August undefined, 2024

WebChromomycin A3 from Streptomyces griseus is an antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities. [ 3] It serves as a fluorescent DNA stain. [ 4] It is useful for the detection of protamine deficiency in sperm chromatin. WebThe biosynthetic gene cluster of the aureolic acid type antitumor drug chromomycin A3 from S. griseus subsp. griseus has been identified and characterized. It spans 43 kb and …

Chromomycin A3 suppresses cholangiocarcinoma growth by induction …

WebApr 27, 2024 · Chromomycin A3 (which is interesting also an antibiotic!), which binds to GC-rich regions of DNA. A Hoechst stain (e.g. 33258 or 33342), that binds to AT-rich regions. Using these DNA stains, we can separate the larger chromosomes from the smaller ones as they will contain more DNA and will thus yield a greater fluorescence signal. WebThis article is cited by 34 publications. Sangita Majee,, Ranjan Sen,, Suranjana Guha,, Dhananjay Bhattacharyya, and, Dipak Dasgupta. Differential Interactions of the Mg2+ Complexes of Chromomycin A3 and Mithramycin with Poly(dG-dC)·Poly(dC-dG) and Poly(dG)·Poly(dC). phone hub albany ga dawson rd

Chromomycin A3 ≥95% (HPLC) Sigma-Aldrich

WebFawn Creek Township is a locality in Kansas. Fawn Creek Township is situated nearby to the village Dearing and the hamlet Jefferson. Map. Directions. Satellite. Photo Map. WebChromomycin A 3 is an anthraquinone antibiotic and antitumor agent isolated from S. griseus that is used as a fluorescent probe for DNA with excitation/emission spectra of 445/575 nm. 1, 2 Its DNA binding is specific to two or more contiguous GC base pairs, which makes it suitable for characterizing heterochromatin in plants with species ... Web其显示的人类染色体带型与Q带或G带相反，异染色质区如染色体的，一般在Q带或G显带中深染，常染色质区浅染，而R带则异染色质区一般浅染，常染色质区深染。. 其他R显带的方法包括用chromomycin A3或olivomycin等荧光素染色，或在细胞周期的合成期（S期）将 ... how do you order from etsy

Chromomycin A3 - an overview ScienceDirect Topics

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WebG-C specific intercalating agents [actinomycin D (AMD) and chromomycin A3 at 1 microM] also prevented ER disappearance; ethidium bromide (EB) and quinacrine were ineffective. AMD and CHX operated immediately after their addition to the medium indicating an inhibitory action on the synthesis of an RNA and/or a peptide with high turnover rate ... Chromomycin A3 (CMA3) or Toyomycin is an anthraquinone antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseus (No. 7). See more In the presence of Mg ions, Chromomycin A3 binds reversibly to DNA, preferentially to contiguous G/C base pairs. When bound to DNA, Chromomycin A3 has a maximum excitation wavelength of 445 See more • in-vitro membrane-impermeant G/C-specific fluorescent DNA-binding dye. • in-vitro antibiotic of gram-positive bacteria, through inhibition of the incorporation of Pi in the RNA. • in-vitro anticancer drug that inhibits RNA synthesis. See more phone htc with keyboardWebDec 4, 2014 · Chromomycin A3 / metabolism Chromomycins / pharmacology HCT116 Cells HL-60 Cells Humans Melanoma / drug therapy* Melanoma / metabolism … phone hub not appearing on my home screen

"WebChromomycin A3 450 570 B, BV G-C Range 4, 6-Diamidino-2-Phenylindole HCl (DAPI) 372 456 U A-T Range Ethidium Bromide 545 605 G, IG DNA•RNA Hoechst 33258 365 465 U A-T Range Hoechst 33342 355 465 U A-T Range Mithramycin 395 570 BV G-C Range Olivomycin 430 ... " - Chromomycin-a3

Chromomycin-a3

Chromomycin A2 Induces Autophagy in Melanoma Cells

http://www.cyto.purdue.edu/cdroms/cyto10a/sponsors/media/dako/mofloxdp/chromosome.pdf WebFeb 25, 1997 · The interaction of the two anticancer antibiotics, chromomycin A 3 and mithramycin, with the polynucleotides poly (dG-dC).poly (dC-dG), representative of B-DNA, and poly (dG)·poly (dC), representative of A-DNA, in the presence of Mg 2+ is studied by spectroscopic techniques such as absorbance, fluorescence, and dircular dichroism (CD).

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WebChromomycin A3 as a fluorescent probe for flow cytometry of human gynecologic samples Author R H Jensen PMID: 70448 DOI: 10.1177/25.7.70448 Abstract Chemical, physical and optical properties of chromomycin A3 are examined so as to ascertain appropriate staining and analysis procedures for flow cytometry of human gynecologic samples.

Webchromomycin A3 Acute Tox. 1; H300 <= 100 % For the full text of the H-Statements mentioned in this Section, see Section 16. SECTION 4: First aid measures 4.1 Description of first-aid measures General advice Show this material safety data sheet to the doctor in attendance. If inhaled After inhalation: fresh air. In case of skin contact WebChromomycin A3. 230752-10MG. 80055-168EA 310.68 USD. 80055-168. Chromomycin A3. Chromomycin A3. Antibiotic that inhibits RNA synthesis. Excitation maximum: …

WebChromomycin A3 (CMA3) Protamination state of the spermatozoa determines its chromatin integrity status. The lesser the protamine content, the poorer the DNA packaging and the higher the sperm DNA damage. CMA3 binds to the sperm DNA deficient of protamine and stains light yellow [74]. The intensity of color is high in sperm with increased prot ... WebFeb 1, 1974 · Chromomycin A3 shows potent antitumor activity against several experimental tumor systems, including Ehrlich carcinoma, Yoshida sarcoma, sarcoma 180, leukemia SN 36 (Tatsuoka et al., 1958), and lymphoid leukemia L1210 and P388 (National Cancer Institute, 1968).

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WebChromomycin A3 from Streptomyces griseus C57H82O26 CID 15953908 - structure, chemical names, physical and chemical properties, classification, patents, literature ... phone hub fall river maWebChromomycin A3 and mithramycin are antibiotics binding preferentially to the GC-rich regions of DNA. They have excitation maxima at 440 nm and emission maxima at 555 and 575 nm, respectively. Unfortunately the low fluorescence intensity … phone hub in albany gaWebChromomycin A3 Revision Date 20-Feb-2024 www.alfa.com Revision Date 20-Feb-2024 Print Date 20-Feb-2024 Revision Summary SDS authoring systems update, replaces ChemGes SDS No. 7059-24-7. Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the how do you order from instacartWebDec 1, 2014 · Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1-related anti-apoptotic proteins Paksiree Saranaruk, R. Kariya, +7 authors K. Vaeteewoottacharn Biology, Chemistry International journal of molecular medicine 2024 TLDR how do you order pizza in meep cityWebChromomycin A₃ - CAS 7059-24-7 - Calbiochem Antitumor antibiotic that inhibits RNA synthesis. A cell-permeable fluorescent dye that can be used with Bisbenzimide H 33258 … how do you order foodWebJan 29, 2024 · CMA3 is an anthraquinone glycosidic antibiotic, produced by Streptomyces griseus ( 21 ). The anti-cancer effects of CMA3 have been proposed since the 1960s ( 22, 23 ). Side effects of CMA3 in advanced breast cancers have interrupted that use ( 24) but it is widely used for DNA staining ( 25 ). how do you order food from amazonWebChromomycin A3 is an antibiotic that binds to the GC-rich sequence of DNA in the presence of divalent cations, inhibiting DNA replication and transcription (1). It is also used as a … how do you order from amazon